Autophagy is a natural and regulated self-degradative process in cells that plays a critical role in balancing sources of energy and removing aggravated proteins, damaged organelles, and pathogens. During autophagy, cells break down and recycle their different parts in order to make new cells. In mesothelioma, autophagy is necessary for[…]
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Bevacizumab – A Positive Treatment with Serious Side Effects
Bevacizumab (Avastin) is commonly viewed as chemotherapy treatment because when administered intravenously, it is particularly effective in controlling such illnesses such as lung cancer and colon cancer. However, it is a bit different than traditional chemotherapy treatments, which directly attack cancer cells. Bevacizumab fights cancer cells by cutting off oxygen[…]
Pevonedistat Alone and in Combination With Chemotherapy in Patients With Mesothelioma
Purpose:The purpose of this study is to test any good and bad effects of activity pevonedistat taken alone, and also to test the safety of pevonedistat in combination with standard chemotherapy, pemetrexed/cisplatin.
November is Lung Cancer Awareness Month
The National Cancer Institute places lung cancer as the leading cause of death from cancer in the United States. One out of every four cancer deaths is attributable to lung cancer, and in 2016 alone The America Cancer Society an estimated 158,080 people passed away from this disease. Lung cancer[…]
Palliative Care for Mesothelioma Patients
What is Palliative Care? For serious illnesses, some patients may receive palliative care, or palliative treatment. Palliative care treats the symptoms of the disease, not the disease itself, in an attempt to provide relief and make the patient as comfortable as possible during their illness. Palliative treatment can be provided[…]
Misconceptions about Mesothelioma
Mesothelioma is lung cancer One of the most common areas of the body where mesothelioma develops is the lung, and because of this, many misunderstand mesothelioma to be a type of lung cancer. In actuality, mesothelioma is cancer of the mesothelium – found in the lining of the heart, lungs,[…]
Pleurectomy and Decortication Improve Survival, but May Impact Quality Of Life
Pleurectomy and Decortication (P/D) is a two-part surgical procedure that removes the pleural lining around the lungs (pleurectomy) and tumors along the surface area of the lung (decortication). To qualify for this surgery, mesothelioma patients must be in overall good health, and in the early stages of the disease. Since[…]
Effect of Expression of CD74 and VEGF on Outcome of Treatment in Patients With Malignant Pleural Mesothelioma
Purpose:his is a prospective study evaluating the effect of expression of CD74 and VEGF on outcome of treatment in patients with malignant pleural mesothelioma receiving Pemetrexed/Platinum protocol. The paraffin blocks of the patients will be tested for CD74 and VEGF before starting treatment using IHC and the results will be correlated with the outcome of treatment during evaluation.
The Effectiveness of Cisplatin and Pemetrexed in Pericardial Mesothelioma
Out of all the types of mesothelioma, pericardial mesothelioma is one of the rarest forms, accounting for only 0.002% of all known diagnosed mesothelioma cases. Mesothelioma is caused by asbestos exposure, and despite this knowledge and years of research, scientists and researchers still do not have a clear answer as[…]
Amosite vs. Chrysotile Asbestos in Peritoneal Mesothelioma
Mesothelioma is rare and aggressive asbestos-caused cancer in which there is no cure. The cancer affects the lining that surrounds various organs and cavities in the body; most tumors are commonly found in the lining of lungs and the chest (the pleura), making up two thirds of all diagnosed cases.[…]
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