From the blog

Genetic Susceptibility in MAlignant Pleural Mesothelioma: Clinical Implication of GermliNE VariaTionS (MAGNETS)

Published: March 28, 2025

Primary Outcome Measures

  • the comparison of prevalence of germline mutations in MPM patients vs asbestos exposed healthy subjects

Secondary Outcome Measures

  • Secondary aim will be the comparison of overall survival (OS) according to mutational status in MPM patients.

Inclusion Criteria

Inclusion Criteria Cohort A:

  • Patient with a documented diagnosis of MPM (any disease stage and independently from chemo line treatment)
  • Age ≥ 18 years (there is no upper age limit).
  • Patient who gives their informed consent to participate in the study

Inclusion Criteria Cohort B:

  • Former asbestos exposed healthy subjects
  • Age ≥ 18 years (there is no upper age limit).
  • Subject who gives their informed consent to participate in the study

Exclusion Criteria

Exclusion Criteria Cohort A:

  • No exclusion criteria

Exclusion Criteria Cohort B:

  • No exclusion criteria
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