Primary Outcome Measures:
- To determine the overall 5-year survival rate. [ Time Frame: 5-years ] [ Designated as safety issue: Yes ]
Secondary Outcome Measures:
- Number of Participants with Adverse Events as a Measure of Safety and Tolerability [ Time Frame: 3 months ] [ Designated as safety issue: Yes ]
Morbidity - Number of Participants with treatment related deaths as a Measure of Safety and Tolerability [ Time Frame: 3 months ] [ Designated as safety issue: Yes ]
Mortality - Recurrence [ Time Frame: 5 years ] [ Designated as safety issue: No ]
Occurence of tumor recurrence
Eligibility & Criteria
- Study Population
- Patients with malignant pleural mesothelioma prsentint at the Deparment of Thoracic Surgery, HSK Wiesbaden
- Inclusion Criteria:
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- Histologically confirmed diagnosis of MPM (all subtypes)
- Clinical T1-3, N0-2, M0 disease.
- No prior treatment for MPM.
- Adequate renal and liver function
- Adequate cardio-pulmonary reserves
- Exclusion Criteria:
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- Patients with unresectable disease
- Patients with an active infection that require systemic treatments
- Patients with a concurrent active malignancy.
- Patients with serious medical illness.
