Primary Outcome Measure:
- Quality of Life [ Time Frame: 6 months ] [Designated as safety issue: Yes] Disease-specific symptom control rate post-treatment, based on Palliation Index [7].
Secondary Outcome Measures:
- Breathing Function [ Time Frame: 6 months ] [ Designated as safety issue: Yes ] Pulmonary function test results at 1, 3 and 6 months post treatment
- Survival/Response Rate [ Time Frame: 6 months ] [ Designated as safety issue: Yes ] performance status at 1, 3 and 6 months post treatment; and overall survival
Eligibility Criteria
- Inclusion Criteria:
-
- Histologic mesothelioma
- Refused/ineligible for surgery or chemotherapy
- Life expectancy >3 months
- Exclusion Criteria:
-
- Contraindications to thoracic radiotherapy
- Unable to lie flat for duration of radiation therapy
