Using maintenance therapy with gemcitabine alongside chemotherapy can help increase survival in patients compared to patients just receiving palliative care. Gemcitabine is an antimetabolite, which prevents cancer cells from dividing into new cancer cells. Chemotherapy is usually the first line treatment for mesothelioma, and if patients are able to receive[…]
From the blog
SMART Mesothelioma Procedure Could Extend the Lives of Certain Mesothelioma Patients
Accelerated high dose radiation before surgery created a 65.9 month survival for mesothelioma patients. They were part of a clinical trial in Toronto at the Princess Margaret Cancer Center. The study is named SMART, an acronym for Surgery for Mesothelioma After Radiation Therapy. There were 96 patients who were treated[…]
Neoadjuvant Toripalimab Combined With Chemotherapy in the Treatment of Malignant Pleural Mesothelioma
This is a single-arm, open, II phase study to evaluate the safety and efficacy of Toripalimab, pemetrexed and carboplatin in the treatment of locally advanced malignant MPM in 15 newly diagnosed patients with locally advanced malignant MPM.
Thoracic Chemotherapy After Surgery Could Help Pleural Mesothelioma Patients Survive Longer
Hyperthermic intrathoracic chemotherapy alongside aggressive therapy (HITHOC) could help extend pleural mesothelioma patient survival. Doctors perform this by circulating a heated high concentration chemotherapy solution in the chest cavity for one hour right after aggressive surgery is performed on a patient. They do this to kill microscopic tumor cells that[…]
Mesothelioma Chemotherapy Resistance Could be Due to Cell Hibernation
Canadian researchers have discovered a cause of chemotherapy resistance in mesothelioma and other cancers. This is great news because this can lead to new treatments being created to combat the incurable cancer. There are other types of treatments approved for mesothelioma, but they might not work and chemotherapy could be[…]
Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors Enriched for Tumors With NF2 Gene Mutations
Primary Outcome Measures Occurrence of Dose Limiting Toxicity [ Time Frame: over the first 21 days of dosing ] Incidence of Adverse and Serious Adverse Events Occurrence of General Toxicity [ Time Frame: through study completion, an average of 30 months ] Incidence of Adverse and Serious Adverse Events, Discontinuations due to Adverse Events and general safety Evaluations[…]
People with an Inherited Mutation on the BLM Gene Could Be More at Risk of Developing Mesothelioma
New research from the University of Hawaii is showing that the inherited mutation on the BLM gene can increase the chance of getting mesothelioma. The researchers sequenced the DNA of 155 mesothelioma patients. People without the BLM gene were more likely to develop mesothelioma, especially when exposed to carcinogenic asbestos[…]
Cholesterol Drugs Called Statins Could Help Extend Mesothelioma Sufferers’ Lives
A group of drugs called statins used for controlling cholesterol are showing that they can help mesothelioma patients taking PD-1 inhibitors survive longer. Researchers in Italy and the Netherlands found this information in an international study of 250 patients. The patients studied either had pleural mesothelioma or non-small cell lung[…]
The ONCOS-102 Vaccine is Still Showing Promising Results
The ONCOS-102 immunotherapy vaccine is still showing promising results. Information from November shows when patients take the treatment with chemotherapy, it helped patients survive a minimum of 18.2 months. The median overall survival was four months better in the experimental group compared to the control group. Targovax, the maker of[…]
Peritoneal Mesothelioma Surgery with More organ Removal Can Help Survival
Mesothelioma surgery that removes more of an organ has been found to extend the survival of patients. It also did not increase the chance of severe complications nor did it change the survival benefits of aggressive surgery on patients with peritoneal mesothelioma. The complex surgery also did not negatively affect[…]
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