Tretinoin, a derivative of vitamin A, is showing potential to enhance the effects of chemotherapy. Combining tretinoin with chemotherapy improved survival rates in mesothelioma in mice. Mesothelioma is a rare type of cancer that is hard to diagnose and treat. It develops from the thin layer of tissue that covers[…]
Pleural Mesothelioma
Limited Surgery to Limit Symptoms of Pleural Mesothelioma
A new clinical trial at the University of Chicago is testing whether a smaller, symptom-focused surgery can help pleural mesothelioma patients maintain quality of life when tumor removal is not possible. This study looks at surgery differently compared to other trials. Rather than focusing first on complete tumor removal, it[…]
Radiomics to Determine Mesothelioma
Malignant mesothelioma is a challenging cancer to treat. New therapies like T cell receptor fusion constructs (TRuCs) show promise. Determining which patients will benefit from these treatments is important. Radiomics, a field that extracts data from medical images, offers a potential solution. Radiomics may predict treatment responses based on imaging[…]
PITAC to Treat Mesothelioma
A Stanford team performed a specialized procedure for pleural mesothelioma for the very first time in North America. It is known as pressurized intrathoracic aerosol chemotherapy (PITAC), and it delivers chemotherapy directly to the chest as a pressurized mist. One doctor knows it as “spray paint chemo.” PITAC is minimally[…]
Pleurectomy/Decortication Surgery Has Low Mortality When Patients are Carefully Selected
A new study out of the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center finds lung-sparing pleurectomy/decortication (P/D) surgery has a very low rate of early mortality. These findings are in direct contrast to those from the MARS2 trial, which reported P/D surgery carried[…]
Tretinoin and Chemotherapy
Tretinoin is a derivative of vitamin A. It has the potential to enhance the effects of chemotherapy. Combining tretinoin with chemotherapy improved survival rates in mesothelioma in mice. Mesothelioma is a rare cancer that is hard to diagnose and treat. It develops on the thin layer of tissue that surrounds[…]
Fibroblasts’ Role in Mesothelioma Development
Malignant mesothelioma is a cancer that is mainly caused by asbestos exposure. Asbestos was once used in construction and other trades. Mesothelioma is a cancer that grows and spreads rapidly, making it dangerous. Treatment options are limited for the cancer. Asbestos is no longer used in many places, but people[…]
The Immune Microenvironment and Pleural Effusion
Malignant pleural effusion is a serious condition where cancer cells spread to the lining of the lungs. This leads to fluid buildup in the chest cavity. Fluid accumulation makes breathing difficult and can be a sign of advanced lung cancer. Pleural effusion is a common symptom of malignant pleural mesothelioma.[…]
Understanding Mesothelioma
Pleural mesothelioma, a cancer of the lining of different areas of the body, including the lungs, is mainly caused by asbestos exposure. This rare cancer is aggressive and challenging to treat. An article provides an overview of pleural mesothelioma, including its causes, symptoms, diagnosis, and treatment options. The main cause[…]
Multimodal Therapy to Treat Mesothelioma
Malignant pleural mesothelioma is a significant health challenge for individuals. Mesothelioma is linked to asbestos exposure and demands innovative treatment strategies. Recent research provides a promising approach to combatting mesothelioma. A multimodal treatment regimen could offer hope and improved outcomes for people battling the disease. A multimodal approach consists of[…]
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