Extended pleurectomy decortication surgery combined with chemotherapy is associated with worse outcomes compared to just chemotherapy alone. Researchers looked at extended pleurectomy and decortication surgery alongside chemotherapy and found that there are worse survival outcomes, a higher chance of serious adverse events, and a diminished quality of life compared to[…]
Pleural Mesothelioma
PARP Inhibitors Could Soon Help Mesothelioma Patients
There is a new treatment involving PARP inhibitors that could potentially benefit mesothelioma patients. PARP stands for Poly (ADP-ribose) polymerase. PARP is typically involved in repairing damaged DNA in cells. It can be useful against side effects from chemotherapy by repairing damaged tumor cells, which helps tumors to continue growing.[…]
Study of Cadonilimab Combined With Bevacizumab and Standard Chemotherapy as First Line Therapy in Unresectable Pleural Mesothelioma
Primary Outcome Measures Objective Response Rate (ORR) defined as the percentage of participants who achieve a best overall response of complete response or partial response assessed according to mRECIST v1.1 for assessment of response in malignant pleural mesothelioma. Up to 36 months Secondary Outcome Measures Progression Free Survival (PFS) defined[…]
Galinpepimut-S and Nivolumab are Effective and Safe for Mesothelioma
The combination of galinpepimut-S and nivolumab is showing promising results for mesothelioma. The study looked at patients who were refractory or relapsed after at least one standard treatment. The combination met safety and efficacy standards for treatment, leading to a completed phase one trial. The median overall survival, which was[…]
Increased Doses of Radiation Improve Survival in Mesothelioma Patients
Researchers are trying to find out if increasing the dose of radiation can improve survival in mesothelioma patients. Radiation is typically seen as a secondary treatment after the combination of chemotherapy, surgery, and immunotherapy. Some doctors do not believe it is a valid treatment for mesothelioma patients because it can[…]
Pembrolizumab and Chemotherapy Improve Survival in Pleural Mesothelioma Patients
The mix of chemotherapy and pembrolizumab extended survival in patients with pleural mesothelioma. It was given as a first line treatment to adults with the cancer. Data shows that pembrolizumab and chemotherapy reduced death by 21 percent compared to chemotherapy alone. Doctors like the combination of pembrolizumab and chemotherapy because[…]
New Rules for Asbestos Abatement in Canada
Canada is creating new rules for asbestos abatement. The government in British Columbia is going to require that companies that perform asbestos abatement have licenses issued by the government for them to operate. The Canadian workers’ compensation statutory agency WorkSafeBC is creating the requirements for companies to be fully licensed[…]
Researchers are Searching for Mesothelioma Biomarkers
Mesothelioma could soon be diagnosed by blood test. Researchers in China have found a new method to analyze blood samples of people with mesothelioma. The researchers used gas chromatography-mass spectrometry (GC-MS). The hope was that the researchers would find biomarkers in the blood of mesothelioma patients that could help with[…]
Finding Out How Asbestos Causes Mesothelioma
Finding Out How Asbestos Causes Mesothelioma Researchers are finding out why it takes a long time for mesothelioma to develop. A study in the Journal of Environmental Research found that the immune system sensing and interacting with particles changes how mesothelioma develops in the body. Researchers found that the main[…]
Researchers are Trying to Find Ways to Prevent Mesothelioma in Asbestos Exposed Individuals
Researchers are trying to find out if mesothelioma can be prevented. Mesothelioma is a cancer of the lining of certain areas of the body including the lungs, abdomen, heart, and testicles. After asbestos exposure, some people develop mesothelioma over a period of many years. Asbestos fibers become lodged in the[…]
