Primary Outcome Measures The analysis of the primary efficacy endpoint will be conducted in all eligible patients, based on the disease control rate (DCR) at 12 weeks according to mRECIST 1.1 for mesothelioma, which was defined as the proportion of patients with compete response (CR), partial response (PR) or stable[…]
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Wildfires Continue to Affect Los Angeles Area
The Los Angeles County Sheriff’s Department issued warnings to Altadena deputies about toxins like asbestos being in the air. Deputies are recommended to wear N95 masks to help prevent toxin inhalation. The Fire Department’s hazmat team in Altadena said the air is hazardous, containing lead, asbestos, and other harmful particulates.[…]
Drug Factories to Treat Mesothelioma
Researchers from Rice University and Baylor College of Medicine developed a new treatment that can eliminate advanced stage mesothelioma tumors in mice within days. The breakthrough treatment used Rice’s cytokine drug factory implants with a checkpoint inhibitor drug. This combination is showing great potential in mesothelioma preclinical trials. The treatment[…]
The Diagnostic Accuracy and Clinical Value of FAPI PET in Pleural Mesothelioma (FAPI-PM)
Primary Outcome Measures The diagnostic performance (sensitivity, specificity, positive predicative value, negative predicative value, and overall diagnostic accuracy – all parameters in %). in of FAPI PET compared to routine imaging modalities, including FDG PET/CT, in suspected PM lesions. Secondary Outcome Measures Calculate the proportion of patients where the location[…]
Decision Making Tools for Mesothelioma
Mesothelioma, a cancer mainly caused by asbestos exposure, is very rare and aggressive. There are many challenges that doctors face when diagnosing, treating, and managing this cancer. Advances in medical technology and data analytics are helping doctors make crucial decisions for patients struggling with the hard to treat and deadly[…]
MARS 2 Trial for Mesothelioma
Malignant pleural mesothelioma is a deadly cancer mainly caused by asbestos exposure. It is a hard-to-treat cancer due to its aggressiveness. The cancer affects the pleura, which is the membrane that covers the lungs. A trial known as MARS 2 tried to find out if extended pleurectomy and decortication could[…]
The Diagnostic Accuracy and Clinical Value of FAPI PET in Pleural Mesothelioma (FAPI-PM)
Primary Outcome Measures Calculate the proportion of patients where the location of the intended pleural biopsy is altered due to FAPI PET/CT replacing FDG PET/CT. Secondary Outcome Measures Compare the cancer stage (IASCL 9th edition TNM-classification) as determined by FAPI PET/CT compared to conventional imaging (including FDG PET/CT) at primary[…]
Improving Mesothelioma Diagnosis
Malignant mesothelioma, an aggressive cancer mainly caused by asbestos exposure, mostly affects the pleura. The pleura is the membrane that surrounds the lungs. It can also harm tissues like the peritoneum, which is a membrane that surrounds the abdomen. Due to its rare nature and shared symptoms with other illnesses,[…]
Changing Gut Bacteria Could Improve Effectiveness of Certain Treatments for Mesothelioma
A new cancer study has found that certain gut bacteria could influence a person’s immune system when fighting mesothelioma, an aggressive cancer of the linings of certain areas of the body including the lungs, abdomen, heart, and testicles. This has led experts to believe that in future cases of mesothelioma,[…]
New Testing for Asbestos in Talc Based Products
In 2023, Congress passed a new law requiring that the U.S. Food and Drug Administration release new industry standards for asbestos testing in products. The agency will require all talc-containing products to be tested for asbestos. This new proposal follows years of lawsuits against Johnson & Johnson and other companies[…]
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