Scientists and researchers from Merck announced an update on their findings for the Phase 1b KEYNOTE-28 study that involves the investigation of the immunotherapy treatment called KEYTRUDA ® (pembrolizumab). The purpose of this study was to evaluate the safety, tolerability, and the anti-tumor activity of KEYTRUDA ® and focused on[…]
Asbestos & Mesothelioma Studies
The First Case of Pulmonary Asbestosis
Asbestosis, a severe and life threatening disease, is directly linked to the inhalation of asbestos fibers. In asbestosis, these fibers make their way to one’s lungs and become embedded in the inner tissue. The tissue then scars causing “fibrosis.” Once the tissue begins to scar, it then starts to harden[…]
Ptac2S Potentially More Effective Than Cisplatin When Fighting Mesothelioma
Malignant Pleural Mesothelioma (MPM) is a rare, aggressive asbestos –related cancer that has a poor survival rate due to the fact that the cancer is hard to detect early, and once detected, has usually spread and is hard to control. Surgery is typically an effective option for removing cancerous cells,[…]
Properties in Red Wine Could Help Fight Mesothelioma
Combining different types of treatment when it comes to treating mesothelioma is common because of how aggressive the cancer can be. While some treatments do prove to be effective, the overall prognosis of an individual with this asbestos-related cancer remains dim. A recent study done in Korea carefully evaluated the[…]
Asbestos Exposure – Can We Really Control It?
Asbestos is typically thought of as a substance that is no longer in use anymore because it is a well-known carcinogen. Asbestos is fire resistant, strong, cheap, abundant, and absorbs sound. It is no wonder it rose to popularity throughout the 20th century since it was so versatile. While asbestos[…]
Measuring the Toxicity of Asbestos
It is a well-known fact that the naturally-occurring mineral asbestos is a carcinogen; linked to lung cancer, asbestosis, and mesothelioma. Once industrial workers began to suffer the effects of asbestos years after being exposed, studies began to focus on the toxicity of the substance. Scientists know that exposure alone is[…]
Mesothelioma and Crohn’s Disease – A Possible Link
Peritoneal mesothelioma is an incredibly rare cancer that makes up about 30% of all mesothelioma cases. This type of mesothelioma affects the peritoneum, which is a protective membrane that surrounds the abdomen and allows the surrounding organs to expand and contract easily. When asbestos fibers become ingested or inhaled, the[…]
Mesothelioma Incidence Rates Around the World
Thousands of people each year are diagnosed with and die from asbestos related diseases such as mesothelioma in the United States each year. But how does that compare to the rest of the world? Even though asbestos is still legal in the United States, the United States’ incidence rate for[…]
The Importance of Clinical Trials – Especially for Mesothelioma Victims
A rare and aggressive malignancy, mesothelioma, is cancer affecting the lining that surrounds various organs and cavities within the body. Mesothelioma gets its name from this lining, which is called the mesothelium. Mesothelioma is a cancer that is strictly caused by asbestos exposure. Victims are typically only given a year, sometimes[…]
Scientists Focus on Enzymes and Proteins to Develop New Treatments
Scientists are continually exploring new opportunities for drugs to combat mesothelioma and recently, scientists have zeroed in on a particular enzyme that is said to be “overexpressed” in pleural mesothelioma. This enzyme, known as orotate phosphoribosyl transferase (OPRT) is believed to curb the development and spread of mesothelioma which would[…]