Primary Outcome Measures Primary endpoint – To evaluate the activity of neo-adjuvant treatment by the determination of pathological complete response rate (pCR) Pathological complete response defined as 0% residual viable tumor cells in the primary tumor and in sampled lymph nodes, following neoadjuvant treatment as assessed by central pathology assessment.[…]
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CARD is Working on New Articles to be Released in 2024
The Center for Asbestos Related Disease is working on new research articles that will be released throughout this year. They will be focusing on asbestos and autoimmune disease. The articles will show results from analyzing the health impact of exposure to amphibole asbestos from Libby, Montana. It can take less[…]
Pembrolizumab and Chemotherapy Improve Survival in Patients
Pleural mesothelioma, a cancer mainly caused by asbestos, is a hard cancer to treat. Diagnosis usually occurs when it is in a late stage, leading to limited treatment options. New clinical trials are always being performed to try to find a new treatment approach that could possibly extend the lives[…]
CIRT Radiation Therapy Beneficial for Lung Cancer Patients
Surgery is usually the first choice for patients and doctors for the treatment of early-stage cancer. There are other options though like radiotherapy. A special type of radiotherapy called Carbon-ion radiotherapy (CIRT)has become popular with doctors. A study in Japan showing how the therapy can benefit patients with early-stage lung[…]
Checkmate743 Showed Higher Toxicity in a Real World Setting
A group of Australian patients receiving Checkmate743 therapy saw higher levels of toxicity compared to CheckMate743 clinical trial patients. Checkmate743 consists of a dual treatment of ipilimumab and nivolumab and is the standard of care for patients with unresectable pleural mesothelioma. Unresectable means patients are not able to receive surgery[…]
A New Biomarker Could Help Doctors Diagnose Mesothelioma
A new biomarker has been found for the diagnosis of mesothelioma by scientists in Japan. Information from this research could revolutionize how mesothelioma is diagnosed and treated in the future. Mesothelioma is a hard cancer to diagnose because it shares symptoms with other cancers. Cancers it can look like include[…]
Johnson & Johnson Will Try to File for Bankruptcy for a Third Time
Johnson & Johnson may try to file bankruptcy for a third time to address its talc liabilities. The company has failed twice before but is looking again to file for bankruptcy under a different corporate structure. There are around 51,000 lawsuits claiming that people who used Johnson & Johnson’s talc-based[…]
Inhibiting YB-1 Can Help Improve Mesothelioma Treatments
Researchers in Vienna, Austria recently found a protein that could help treat mesothelioma patients. Researchers found the oncoprotein YB-1 which, when targeted, could make pleural mesothelioma more sensitive to chemotherapy and radiotherapy. The results of the study were published in the medical journal “Cancer Letters.” The study builds on earlier[…]
Teachers in Philadelphia are Suing for Being Punished for Asbestos Protest
Three teachers recently filed a lawsuit over their first amendment right to publicly demand answers about asbestos inside classrooms. They claim their rights were violated when they were punished for protesting in 2021. As part of a protest, they worked outside during teacher only workdays to protest their risks of[…]
There are Stricter Regulations for Manufacturers of Asbestos
Now that the final reporting from the U.S. Environmental Protection Agency’s Toxic Substances Control Act is completed, asbestos manufacturers and processors are under stricter regulations. This is all due to the EPA mandating the reporting and record-keeping of uses of asbestos by companies that manufacture, import, or process asbestos or[…]
