A YAP/TEAD inhibitor is showing promising results for people with mesothelioma and other cancers. The inhibitor, known as VT3989, was well tolerated and had good anti-tumor effects in cancer patients with mesothelioma and NF2 mutations. Results were recently published from the first human study. Seven of 69 patients had radiological[…]
New Study
Impact on Survival When People Have a Second Cancer in Addition to Mesothelioma
Researchers decided to look at the relationship between having mesothelioma in addition to a second cancer and their impact on survival. Researchers found that a second cancer did not affect survival for most patients with mesothelioma, but for patients with a specific type of mesothelioma, survival was affected. Mesothelioma is[…]
Cytoreductive Surgery and Chemotherapy Improved for Mesothelioma
Improvements have been made for cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC). This treatment combination is typically performed on people with cancers in the abdominal region. One such cancer is peritoneal mesothelioma. Peritoneal mesothelioma is a cancer of the lining of the abdomen caused by asbestos exposure. Peritoneal mesothelioma is[…]
Keytruda Helps Improve Survival for Mesothelioma When Used Alongside Chemotherapy
Keytruda is showing promising results for the treatment of pleural mesothelioma. Researchers found that the combination of Keytruda (pembrolizumab) and chemotherapy lead to a better survival in patients versus chemotherapy alone. Mesothelioma is a hard-to-treat cancer with no cure. It can be found in the linings of the lungs, abdomen,[…]
Mesothelioma Global Impact Study
A study looking at the global impact of mesothelioma was recently published. Researchers examined age, sex, and geographic locations to see the risk of asbestos at the population level. It was discovered that Northern Europe, Australia, and New Zealand had the highest rates of mesothelioma. The age standardized rate of[…]
BAP1 and Mesothelioma Risk
Researchers have found at least one way that asbestos causes mesothelioma. The disease is linked to the HMGB1 protein. Researchers looked at a mesothelioma epidemic in Türkiye, noting that in some families, up to 50 percent develop mesothelioma. Family members passed the likelihood of mesothelioma from generation to generation. Families[…]
Accelerated Hypofractionated Radiotherapy for Mesothelioma
A recent study from Italy found that accelerated hypofractionated radiotherapy could be an effective treatment for mesothelioma. This is good news for people suffering from the rare and aggressive cancer. The patients in the study had higher chances of living longer while also having a lower risk of the disease[…]
A Vaccine to Prevent and Treat Mesothelioma Could be Possible in the Future
A vaccine for lung cancer could possibly lead to a vaccine for mesothelioma. The lung cancer immunotherapy drug CIMAvax-EFG is making great progress, and because of this progress, researchers are utilizing the treatment in new ways. The researchers are trying to see how the vaccine can be used to prevent[…]
Gene Suppressor Therapy Could Improve Survival for Mesothelioma Patients
New mesothelioma research is being performed at The Netherlands Cancer Institute. The researchers are looking at new combinations of medications to be used on patients that have mesothelioma with BAP1 genetic mutations. More than half of patients with mesothelioma have changes in the BAP1 tumor suppressor gene. When the BAP1[…]
Using MicroRNA as a Biomarker to Diagnose Mesothelioma
The early diagnosis and treatment of mesothelioma is critical for extending survival in patients. Researchers in Italy may have found a helpful biomarker to catch mesothelioma earlier, up to five years before a clinical diagnosis. This is helpful because once mesothelioma is diagnosed, it is hard to treat due to[…]
