Mesothelioma is a rare and deadly cancer of the mesothelium, which is a membrane that surrounds multiple organs including the lungs and abdomen. The best thing for patients after a mesothelioma diagnosis is treatment in the form of chemotherapy, surgery, immunotherapy, or multiple treatments together. This can be mentally and[…]
New Study
A Gene Therapy Could Improve Survival for Mesothelioma
Results from a new study involving a genetic therapy for pleural mesothelioma have been submitted at the University of Leicester. Researchers at the United Kingdom university designed a treatment to match specific genetic profiles to individual patients. There are promising results from the study, which had patients who received first[…]
Tremelimumab and Durvalumab Combination Can Improve Mesothelioma Survival
Studies show that durvalumab and tremelimumab work very well together while treating mesothelioma. A phase I clinical trial was performed at the Baylor College of Medicine in conjunction with Baylor St. Luke’s Medical Center. Durvalumab is an immunotherapy drug known as a PD-1/PD-L1 checkpoint inhibitor. It works by blocking the[…]
Researchers are Studying the Mesothelioma Tumor Microenvironment
A new study is showing how the tumor microenvironment helps mesothelioma progress and survive in the body. Mesothelioma tumors create a complex microenvironment surrounding themselves. The microenvironment is simply the area surrounding the tumors. The new study shows that the microenvironment that mesothelioma tumors create assists cancer initiation and progression.[…]
Different Levels of Pleurectomy and Decortication Surgery can Save Mesothelioma Patients’ Lives
Italian researchers believe that lung sparing surgery can improve survival in mesothelioma patients, even when surgeries are more conservative. Pleurectomy and decortication is the surgery that spares the lungs. It is less comprehensive than the surgery that removes the lungs, which also makes it less dangerous to patients. Doctors at[…]
A Virus that Affects Goats Could Help Treat Mesothelioma
Mesothelioma, a cancer of the membrane that surrounds the lungs, abdomen, heart, and testicles is a very aggressive cancer. It spreads very quickly and when the tumors grow big enough, they crowd out organs and make it hard for people to breath. Mesothelioma sufferers can experience coughing, chest pain, and[…]
Epigenetics Used to Improve Immunotherapy for Mesothelioma
Researchers are looking into changing mesothelioma cells to make them more susceptible to immunotherapy. Mesothelioma is a hard cancer to treat, so new approaches need to be developed to try to lengthen and improve mesothelioma patients’ lives. Immunotherapy can work well for some, but for others it does very little,[…]
Assessment of Histologic Prognostic Factors in Peritoneal Malignant Mesothelioma
Primary Outcome Measures Assessment of pronostic impact of nuclear grade in comparison with combined grade in peritoneal malignant mesothelioma [ Time Frame: 3 months to 4 years ] Assessment by the review of pathologists Inclusion Criteria peritoneal malignant mesothelioma Exclusion Criteria opposition to reuse personnal data
LMB-100 and Ipilumab Combination Being Tested for Pleural and Peritoneal Mesothelioma
The National Cancer Institute just started a study to see if it could make immunotherapy more potent for treating mesothelioma. The study combines a manmade protein that kills cancer cells called LMB-100 and an immunotherapy drug called ipilumab. The problem with current immunotherapy treatments is they do not work well[…]
GPX-1 Could be used as a Biomarker for Mesothelioma
An enzyme that helps clean up the byproducts of cellular oxidation could potentially be a biomarker for pleural mesothelioma. People with very small amounts of the enzyme were found to survive longer than people who have higher levels of the enzyme. The enzyme is Glutathione peroxidase-1 (GPX-1). It can be[…]
