Novel Treatments & Drugs

Why Patients Quit PIPAC for Mesothelioma

PIPAC, or pressurized intraperitoneal aerosol chemotherapy, is showing promising results for mesothelioma, but patients don’t finish all their sessions. This is a problem because the patients then limit the effectiveness of their treatment. Researchers in France decided to figure out why patients are quitting their treatments early. Mesothelioma is a[…]

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Pembrolizumab and Chemotherapy Improve Survival in Pleural Mesothelioma Patients

The mix of chemotherapy and pembrolizumab extended survival in patients with pleural mesothelioma. It was given as a first line treatment to adults with the cancer. Data shows that pembrolizumab and chemotherapy reduced death by 21 percent compared to chemotherapy alone. Doctors like the combination of pembrolizumab and chemotherapy because[…]

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Researchers are Trying to Find Ways to Prevent Mesothelioma in Asbestos Exposed Individuals

Researchers are trying to find out if mesothelioma can be prevented. Mesothelioma is a cancer of the lining of certain areas of the body including the lungs, abdomen, heart, and testicles. After asbestos exposure, some people develop mesothelioma over a period of many years.  Asbestos fibers become lodged in the[…]

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Researchers Tried to Determine Which Second Line Treatment is Best for Mesothelioma

Researchers from China tried to determine whether immunotherapy or chemotherapy is better as a second line treatment option for relapsed pleural mesothelioma. There is no current standard therapy for people whose mesothelioma comes back, which makes it hard for doctors to make treatment decisions for patients. Mesothelioma is very aggressive,[…]

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YAP/TEAD Inhibitor is Showing Promising Results for Mesothelioma and NF2-Mutant Cancers

A YAP/TEAD inhibitor is showing promising results for people with mesothelioma and other cancers. The inhibitor, known as VT3989, was well tolerated and had good anti-tumor effects in cancer patients with mesothelioma and NF2 mutations. Results were recently published from the first human study. Seven of 69 patients had radiological[…]

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Keytruda Helps Improve Survival for Mesothelioma When Used Alongside Chemotherapy

Keytruda is showing promising results for the treatment of pleural mesothelioma. Researchers found that the combination of Keytruda (pembrolizumab) and chemotherapy lead to a better survival in patients versus chemotherapy alone. Mesothelioma is a hard-to-treat cancer with no cure. It can be found in the linings of the lungs, abdomen,[…]

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Accelerated Hypofractionated Radiotherapy for Mesothelioma

A recent study from Italy found that accelerated hypofractionated radiotherapy could be an effective treatment for mesothelioma. This is good news for people suffering from the rare and aggressive cancer. The patients in the study had higher chances of living longer while also having a lower risk of the disease[…]

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Gene Suppressor Therapy Could Improve Survival for Mesothelioma Patients

New mesothelioma research is being performed at The Netherlands Cancer Institute. The researchers are looking at new combinations of medications to be used on patients that have mesothelioma with BAP1 genetic mutations. More than half of patients with mesothelioma have changes in the BAP1 tumor suppressor gene. When the BAP1[…]

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Using MicroRNA as a Biomarker to Diagnose Mesothelioma

The early diagnosis and treatment of mesothelioma is critical for extending survival in patients. Researchers in Italy may have found a helpful biomarker to catch mesothelioma earlier, up to five years before a clinical diagnosis. This is helpful because once mesothelioma is diagnosed, it is hard to treat due to[…]

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Cytokine Factories to Treat Pleural and Peritoneal Mesothelioma

A new study from Rice University in Houston is showing promising results for mesothelioma. It utilizes the immune system to fight cancer cells. The protein that is being studied is interleukin 2 (IL2), which is a protein that regulates white blood cells through the use of cytokines, a cell signal[…]

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