From the blog

Pulmonary Interstitial Lymphography in Early Stage Lung Cancer

Published: August 26, 2010

Primary Outcome Measures:

  • – Feasibility and safety of identification of primary nodal drainage for purpose of radiation therapy targeting [ Time Frame: 15 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

  • – Feasibility of incorporating primary nodal drainage into radiation therapy planning process [ Time Frame: 15 months ] [ Designated as safety issue: No ]


Inclusion Criteria:
  • Either
    1. Established primary lung cancer/ cancer metastatic to lung, OR
    2. Lesion suspicious for malignancy in lung, according to the following criteria:
      1. Histopathologically confirmed lung cancer or cancer metastatic to lung, OR
      2. Plan for biopsy of suspicious lung mass based on imaging (growth on serial CT scan or nodule/mass with focal hypermetabolism on FDG-PET scan), OR
      3. Known metastatic cancer, with metastases to the lung based on imaging
  • Age > 18 years old
  • Eastern Clinical Oncology Group performance status 0, 1 or 2 (Appendix IV)
  • No prior surgery, chemotherapy, or radiation for the current lung tumor
  • Both men and women and members of all races and ethnic groups are eligible for this trial.
Exclusion Criteria:
  • Prior radiotherapy to thorax
  • Allergy to iodine
  • Contraindication to receiving radiotherapy, unless undergoing surgery
  • Women who are pregnant
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