Pulmonary Interstitial Lymphography in Early Stage Lung Cancer

Primary Outcome Measures:

• – Feasibility and safety of identification of primary nodal drainage for purpose of radiation therapy targeting [ Time Frame: 15 months ] [ Designated as safety issue: No ]
  

Secondary Outcome Measures:

• – Feasibility of incorporating primary nodal drainage into radiation therapy planning process [ Time Frame: 15 months ] [ Designated as safety issue: No ]

Criteria

Inclusion Criteria:

• Either
  1. Established primary lung cancer/ cancer metastatic to lung, OR
  2. Lesion suspicious for malignancy in lung, according to the following criteria:
     1. Histopathologically confirmed lung cancer or cancer metastatic to lung, OR
     2. Plan for biopsy of suspicious lung mass based on imaging (growth on serial CT scan or nodule/mass with focal hypermetabolism on FDG-PET scan), OR
     3. Known metastatic cancer, with metastases to the lung based on imaging
• Age > 18 years old
• Eastern Clinical Oncology Group performance status 0, 1 or 2 (Appendix IV)
• No prior surgery, chemotherapy, or radiation for the current lung tumor
• Both men and women and members of all races and ethnic groups are eligible for this trial.

Exclusion Criteria:

• Prior radiotherapy to thorax
• Allergy to iodine
• Contraindication to receiving radiotherapy, unless undergoing surgery
• Women who are pregnant