Researchers are trying to determine if a breath test can detect malignant pleural mesothelioma in patients exposed to asbestos. Early results are promising, but more research is needed to see what can be done for patients. The study, which is known as MESOBREATH 5, uses a test to detect volatile[…]
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Extended Pleurectomy and Decortication Surgery Worse than Just Receiving Chemotherapy
Extended pleurectomy decortication surgery combined with chemotherapy is associated with worse outcomes compared to just chemotherapy alone. Researchers looked at extended pleurectomy and decortication surgery alongside chemotherapy and found that there are worse survival outcomes, a higher chance of serious adverse events, and a diminished quality of life compared to[…]
CARD Clinic in Libby Files for Bankruptcy
The Center for Asbestos Related Disease in Libby, Montana recently filed for Chapter 11 bankruptcy protection. The center, known as CARD, had to pay $6 million because it submitted 337 false asbestos claims. The lawsuit revealing this information was filed by the BNSF Railway under the Federal False Claims Act.[…]
Orphan Drug Status Given to New Treatment for Mesothelioma
A new treatment for mesothelioma was recently given orphan drug status by the United States FDA. The company given orphan drug status is known as Avenge Bio, which is a biotechnology company working to create a new immunotherapy treatment regimen. It announced that it was given orphan drug status back[…]
Genetic Testing for Mesothelioma
A new study is showing that running genetic tests on mesothelioma patients could be useful. The study was conducted at the University of Chicago and University of Wisconsin. While the main cause of mesothelioma is asbestos, genetic mutations can also influence people getting mesothelioma. Doctors do not usually test mesothelioma[…]
Biomarkers Could be Used to Monitor Mesothelioma Patients
Researchers from Türkiye believe that biomarkers in the blood can help determine if patients are responding well to their treatment. Biomarkers are molecules that can let doctors know what is happening in the body. Even a small number of biomarkers could potentially help point doctors to progress being made in[…]
New Rules Regarding Reporting of Asbestos
The U.S. Environmental Protection Agency announced its final rule requiring comprehensive reporting of asbestos. The rule requires that importers and manufacturers of asbestos related products report information including use and exposure information from the past four years. The new rule was issued under the Toxic Substances Control Act. The reporting[…]
Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma
Primary Outcome Measures To determine stabilization or disease improvement rates in participants with early-stage mesotheliomas arising in the context of BAP1 CPDS following decitabine/cedazuridine treatment Secondary Outcome Measures To evaluate the safety of decitabine/cedazuridine To determine PFS in participants receiving decitabine/cedazuridine Inclusion Criteria Participants with history of germline BRCA1-Associated Protein-1[…]
PARP Inhibitors Could Soon Help Mesothelioma Patients
There is a new treatment involving PARP inhibitors that could potentially benefit mesothelioma patients. PARP stands for Poly (ADP-ribose) polymerase. PARP is typically involved in repairing damaged DNA in cells. It can be useful against side effects from chemotherapy by repairing damaged tumor cells, which helps tumors to continue growing.[…]
Marine Bacteria Could Potentially Detoxify Asbestos
There may be a new way to detoxify asbestos. Researchers at the University of Pennsylvania’s Department of Earth and Environmental Science are using bacteria from extreme marine environments. They are using a technique called bioremediation, which is a form of biotechnology that uses living organisms to remove toxins or contaminants[…]
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