New mesothelioma research is being performed at The Netherlands Cancer Institute. The researchers are looking at new combinations of medications to be used on patients that have mesothelioma with BAP1 genetic mutations. More than half of patients with mesothelioma have changes in the BAP1 tumor suppressor gene. When the BAP1[…]
Gene Therapy
Enzyme and Chemotherapy Combination for Mesothelioma
Pleural mesothelioma sufferers could improve their survival by as much as 30 percent when treated with the latest cancer enzyme and chemotherapy. In a recent study known as ATOMIC Meso, ADI-PEG 20 showed effectiveness when used for sarcomatoid and biphasic mesothelioma, the two most resistive to treatment. The enzyme is[…]
An Inhalable Gene Therapy is Being Tested for Mesothelioma
An inhalable gene therapy could potentially be approved for use in mesothelioma patients. Researchers in Japan have created two different tumor suppressing drugs that work by targeting genetic mutations. The drugs were created for non-small cell cancer and pleural mesothelioma. They are both doing well in the laboratory. The drugs[…]
A Gene Therapy Could Improve Survival for Mesothelioma
Results from a new study involving a genetic therapy for pleural mesothelioma have been submitted at the University of Leicester. Researchers at the United Kingdom university designed a treatment to match specific genetic profiles to individual patients. There are promising results from the study, which had patients who received first[…]
Epigenetics Used to Improve Immunotherapy for Mesothelioma
Researchers are looking into changing mesothelioma cells to make them more susceptible to immunotherapy. Mesothelioma is a hard cancer to treat, so new approaches need to be developed to try to lengthen and improve mesothelioma patients’ lives. Immunotherapy can work well for some, but for others it does very little,[…]
CAR T-Cell Therapy Could Soon be used on Mesothelioma Patients
An immunotherapy treatment that utilizes T cells to fight cancer may soon be covered by Medicare for mesothelioma patients. Immunotherapy is still an emerging set of cancer treatments that utilizes the patient’s own immune system to fight and kill cancer cells. The specific treatment that uses T cells is called[…]
Phase III Clinical Trial for Mesothelioma Available in 50 Locations Across the Globe
A Phase III clinical trial is now underway in the pivotal study of interferon alfa-2b gene therapy in pleural mesothelioma. After promising results from the Phase II clinical trial, scientists and researchers are hopeful they are just one step away from FDA approval for this cancer treatment that is over[…]
FDA Approves Genetic-Based Cancer Treatment that Could Help Mesothelioma Patients
Correcting genes that allow cancerous tumors to grow is the basis behind gene therapy, a relatively new treatment that is largely in experimental stages. The initial goals of gene therapy were to address hereditary genetic disorders, but other factors such as the sun, smoking, chemical exposure, etc., can all damage[…]
Effective Chemotherapy May Rest Upon Reducing Overactive Enzyme
Chemotherapy for mesothelioma patients has been notoriously difficult and the cancer continues to be overwhelmingly unresponsive to such treatment in many cases. However, researchers and scientists have been continually investigating new techniques that involve adjusting how chemotherapy reacts on a cellular level. A study published in the Frontiers in Pharmacology[…]
Gene Therapy and DNA Sequencing for Malignant Mesothelioma
Genes are the basic unit of DNA that creates unique proteins used for specific cellular function. The expression of that gene creates an effect and if a gene cannot make a specific protein, this can lead some health risks or problems. A multifactorial disorder, like cancer, heart disease, and diabetes,[…]
