The mix of chemotherapy and pembrolizumab extended survival in patients with pleural mesothelioma. It was given as a first line treatment to adults with the cancer. Data shows that pembrolizumab and chemotherapy reduced death by 21 percent compared to chemotherapy alone. Doctors like the combination of pembrolizumab and chemotherapy because[…]
Mesothelioma
New Rules for Asbestos Abatement in Canada
Canada is creating new rules for asbestos abatement. The government in British Columbia is going to require that companies that perform asbestos abatement have licenses issued by the government for them to operate. The Canadian workers’ compensation statutory agency WorkSafeBC is creating the requirements for companies to be fully licensed[…]
Researchers are Searching for Mesothelioma Biomarkers
Mesothelioma could soon be diagnosed by blood test. Researchers in China have found a new method to analyze blood samples of people with mesothelioma. The researchers used gas chromatography-mass spectrometry (GC-MS). The hope was that the researchers would find biomarkers in the blood of mesothelioma patients that could help with[…]
Finding Out How Asbestos Causes Mesothelioma
Finding Out How Asbestos Causes Mesothelioma Researchers are finding out why it takes a long time for mesothelioma to develop. A study in the Journal of Environmental Research found that the immune system sensing and interacting with particles changes how mesothelioma develops in the body. Researchers found that the main[…]
Researchers are Trying to Find Ways to Prevent Mesothelioma in Asbestos Exposed Individuals
Researchers are trying to find out if mesothelioma can be prevented. Mesothelioma is a cancer of the lining of certain areas of the body including the lungs, abdomen, heart, and testicles. After asbestos exposure, some people develop mesothelioma over a period of many years. Asbestos fibers become lodged in the[…]
Indiana Warehouse Fire Deposited Asbestos-Contaminated Debris
An Indiana warehouse fire led to asbestos contaminated debris falling onto the surrounding community. The debris landed on school yards, playgrounds, day cares, and private homes. Areas affected by the falling debris include Richmond, Indiana, and nearby areas in Ohio. Asbestos fibers are weightless, so smoke carried the fibers, which[…]
Researchers Tried to Determine Which Second Line Treatment is Best for Mesothelioma
Researchers from China tried to determine whether immunotherapy or chemotherapy is better as a second line treatment option for relapsed pleural mesothelioma. There is no current standard therapy for people whose mesothelioma comes back, which makes it hard for doctors to make treatment decisions for patients. Mesothelioma is very aggressive,[…]
Studying the Clinical Trial Experiences of Patients With Mesothelioma
Primary Outcome Measures Rate of patients who decide to enroll in a mesothelioma medical study. [ Time Frame: 3 months ] Number of mesothelioma patients who remain in clinical trial until completion. [ Time Frame: 12 months ] Inclusion Criteria Must have a medical diagnosis of mesothelioma that has been confirmed by a physician. Aged ≥ 18 years[…]
YAP/TEAD Inhibitor is Showing Promising Results for Mesothelioma and NF2-Mutant Cancers
A YAP/TEAD inhibitor is showing promising results for people with mesothelioma and other cancers. The inhibitor, known as VT3989, was well tolerated and had good anti-tumor effects in cancer patients with mesothelioma and NF2 mutations. Results were recently published from the first human study. Seven of 69 patients had radiological[…]
A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors
Primary Outcome Measures Phase 1 (Dose Escalation): Incidence of adverse events [ Time Frame: From CTX131 infusion up to 28 days post-infusion ] Defined as dose-limiting toxicities Phase 2 (Cohort Expansion): Objective response rate (ORR) [ Time Frame: From CTX131 infusion up to 60 months post-infusion ] ORR based on Independent Review Committee (IRC) assessment, defined as the[…]
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