From the blog

3D Printing and Optical Scanning Could Help Mesothelioma Treatment

Published: September 25, 2026

New technologies offer hope for more effective treatments for malignant pleural mesothelioma and other hard-to-treat cancers. One innovation is the use of 3D printing and optical scanning. These new technologies refine photodynamic therapy, a promising approach for mesothelioma management. Photodynamic therapy uses the power of light to target and destroy cancer cells. Activating a photosensitizer with light leads to the death of cancerous tissue. This therapy offers a targeted and less invasive option for treating mesothelioma.

Mesothelioma is aggressive, often diagnosed late, and challenging to treat. Traditional approaches like surgery alone have limited success rates. Photodynamic therapy, when combined with surgery, shows promise in improving outcomes. Accurately delivering the right dose of light to the affected area is crucial for its success. Advanced 3D printing techniques have helped in this area. They create precise models that mimic the intricate structures of the human body. By printing models of the pleural cavity, where mesothelioma occurs, researchers can better understand its complexities. They can also tailor treatment plans accordingly. Researchers first digitally reconstructed the lung cavity using 3D printing and optical scanning. These models are then compared to CT scans to ensure accuracy. By representing the anatomy, these models help in planning therapy dosages.

The reconstructed models show exceptional anatomical precision while helping doctors plan precise dosage calculations. These models enhance treatment planning. They also serve as valuable tools for education and equipment calibration. This research marks a significant step forward in personalized medicine for mesothelioma patients. 3D printing and optical scanning technologies also open new improvements for mesothelioma treatment. Machine learning algorithms may lead to more effective and tailored therapies. Real-time monitoring systems can enhance treatment delivery and minimize side effects.

The combination of 3D printing and optical scanning holds great promise in refining photodynamic therapy for mesothelioma. These technologies improve dosage precision and treatment planning. Together, they offer hope for better outcomes and improved quality of life. As research continues, we look forward to seeing how these advancements will transform mesothelioma treatment in the years to come.

Research for mesothelioma and other hard-to-treat cancers is crucial for the advancement of survival and quality of life of patients. Without research, we would not be where we are today with mesothelioma treatment. Mesothelioma once had a much shorter survival time, but with advancements in treatment, survival time has improved. Research needs to continue for mesothelioma. If this happens, then maybe one day mesothelioma could be a curable cancer with much better quality of life and survival times after diagnosis.

Source:
Dennis Sourvanos et al., “Three-dimensional printing of the human lung pleural cavity model for PDT malignant mesothelioma” Photodiagnosis and Photodynamic Therapy (April 2024). [Link]
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