A new treatment utilizing CAR-T cell therapy could help prevent mesothelioma cells from protecting themselves. The treatment, called UCARTMESO, is being developed by the French biopharmaceutical company Cellectis. The treatment works by targeting cells that overexpress mesothelin, which is an antigen that prevents cells from sending immune suppressive signals. A[…]
Novel Treatments & Drugs
SQAP Used Alongside Radiation to Treat Mesothelioma
A chemical that makes cancer cells more sensitive to radiation could potentially help patients with mesothelioma. Radiotherapy utilizes ionizing radiation to damage the DNA of cancer cells, which affects their ability to reproduce and form tumors. Radiation is not always used for mesothelioma patients because mesothelioma cells can be immune[…]
Researchers Could Target Neuron Cells to Fight Mesothelioma
Researchers have potentially found a new way to treat cancer by targeting nerve cells. Researchers at Technion, the Israel Institute of Technology, conducted the study that is now published in the Science Advances journal. The research targets neurons, which promote tumor growth. The researchers assumed that once tumor nerve cells[…]
Quinacrine Combined with Cisplatin Can Help Fight Mesothelioma Cancer Cells
Mesothelioma patients with a gene mutation could benefit greatly from using an anti-malaria drug called quinacrine. Quinacrine is known by the brand name Atabrine. For a long time, it was the primary anti-malaria drug, but it has been replaced by the preferred chloroquine. Researchers at Penn State found that quinacrine[…]
A Cancer Fighting Gel Can Help Mesothelioma Patients
A cancer fighting gel that is applied directly to tumors could help mesothelioma patients. Researchers in Maryland tested the treatment on animals with mesothelioma tumors. The tumors responded even after one application. The gel could be used alone or could be used while doctors are performing surgery on mesothelioma. It[…]
Ramucirumab and Gemcitabine are Showing Promising Results as a Second Line Treatment for Pleural Mesothelioma
Combining the drug ramucirumab with the chemotherapy drug gemcitabine is showing to be a successful second line treatment for pleural mesothelioma. Ramucirumab is a type of immunotherapy drug called a monoclonal antibody, which targets and restricts proteins that stimulate blood vessel growth in tumors. The Lancet Oncology published the results[…]
HITHOC After Pleurectomy and Decortication Surgery Can Improve Survival
There are some good results coming from a German study looking at Pleurectomy and Decortication surgery (P/D) being combined with HITHOC. Pleurectomy surgery is surgery that removes mesothelioma tumors but leaves the lung intact while HITHOC is a method of adding heated chemotherapy to the pleural area, sparing the rest[…]
ONCOFID-P Was Given Orphan Drug Status to Treat Pleural Mesothelioma
Pleural mesothelioma could soon have a new approved treatment option. The Food and Drug Administration just granted orphan drug status to ONCOFID-P for the treatment of the cancer. It is currently being studied for invasive bladder cancer, but data from lab and mice models is showing it could be beneficial[…]
Researchers are Trying to Find New Treatments to Combine with Tumor Treating Fields
Tumor Treating Fields were approved for treating mesothelioma, and while they are effective, researchers want to make them more effective for the cancer. A researcher at the Humanitas University in Milan is studying different drug combinations to use with Tumor Treating Fields. The goal is to find a drug that[…]
CAR-T Cell Therapy and Keytruda is Showing Real Promise
Researchers at the Memorial Sloan Kettering Cancer Center are experimenting with a combination of CAR-T cell therapy and Keytruda, a PD-1 blocker for the treatment of pleural mesothelioma. This is the first time that these two therapies have been combined. The results were recently published in Cancer Discovery. Mesothelioma is[…]
